Bulletin of cardiovascular diseases
Constant high levels of stress can disturb the blood flow and blood pressure and can damage vessels, and you may experience dizziness, extreme fatigue, or body aches with no wish to get out of bed. This stress-induced fatigue can make your blood pressure high and needs to be monitored.
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Bulletin of cardiovascular diseases
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Описание Bulletin of cardiovascular diseases
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Bulletin of cardiovascular disease: A silent epidemic in our society Cardiovascular diseases are among the leading causes of death in the world and Germany is no exception. According to statistics from the Robert Koch Institute, about 30% of all deaths annually in Germany on diseases of the circulatory system. These Figures clearly show that The risk is real, and it affects all of us. What lies behind the term cardiovascular disease? This includes heart attacks, strokes, high blood pressure, heart rhythm disorders, and vascular disorders. Often, these diseases develop gradually and unnoticed for a long time. Many Sufferers feel only symptoms, if the damage is already significant. Why are these diseases are so dangerous? The main reasons lies in the variety of risk factors, in our modern lives: Unhealthy diet: Too much salt, sugar and saturated fatty acids, the heart and blood vessels strain. Lack of exercise: A sedentary lifestyle promotes Obesity and weakens the tissues of the heart muscle. Stress: Chronic Stress increases blood pressure and is a burden on the heart permanently. Smoking and alcohol intake: nicotine and alcohol damage the blood vessels and increase the risk for heart attack and stroke. Genetic Disposition: A family history can increase the risk as well. Prevention instead of reaction This ongoing challenge is to raise the awareness of the population for the theme. Many people underestimate their own risk. The medicine shows clear: cardiovascular diseases are to a large extent avoidable. Simple measures can reduce the risk significantly: Regular physical activity (at least 150 minutes of moderate load per week). A balanced diet with lots of fruits, vegetables, whole grains and healthy fats. Reduction of salt and sugar in the diet. Not Smoking and moderate use of alcohol. Regular health checks for blood pressure control, cholesterol levels and blood sugar. The way to a healthier future The incidence of cardiovascular reduce diseases sustainable, it needs not only individual efforts, but also social measures. A healthy diet should be easily accessible, sports activities need to be promoted, and prevention campaigns need to reach the population. Every individual can make a contribution: he informed his family about the risks, healthier life habits established and, if necessary, seek medical advice seek. The health of our cardiovascular system is to a large extent in our own hands. It is at the time, the issue of the cardiovascular diseases face — before it is too late.
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Ang pagkontrol sa presyon ay isang napakahalagang gawain, dahil ang pag-inom ng mga tableta na nakakatulong sa pagpapanatili ng normal na mga indikador ay maaaring magbigay ng araw-araw na komportableng buhay, upang maiwasan ang panganib ng hypertensive crisis, atake sa puso, at stroke. Ang mga gamot para sa kontrol ng presyon ay medyo malawakang makukuha sa mga botika, pero tanging ang doktor lang ang makakapili ng tamang gamot na angkop sa therapy. Lahat ng grupo ng gamot para pababain ang presyon ay may iba't ibang mekanismo ng epekto, side effects, at may kaunting posibilidad ng pagkadepende. Ang tamang pagpili ng gamot ay nagbibigay ng mabilis at tuloy-tuloy na resulta, at ang eksperimento sa sarili sa pag-inom ng gamot ay may mataas na posibilidad ng biglaang karamdaman, sakit sa puso at daluyan ng dugo, at sa matinding kaso, maaaring magdulot ng kamatayan. Отзывы о Bulletin of cardiovascular diseases
Анна: A sedentary lifestyle, alcohol, and cigarette consumption increase body weight which in turn hinders healthy blood circulation and strength of arteries and veins. This results in high blood pressure. So, if you’re overweight, you need to monitor your blood pressure frequently.
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Ang mga tableta para pababain ang presyon ng dugo ay natural na nakakatulong para mabilis itong bumalik sa normal, pero inirerekomenda rin na baguhin ang pamumuhay. Ang malusog na pagkain, kontrol sa timbang, regular na ehersisyo, at pag-iwas sa paninigarilyo at alak ay magagandang paraan para maiwasan ang mataas na presyon ng dugo. Siguraduhing mas kaunting sodium (hal. asin) at mas maraming potassium (mga saging, spinach, broccoli) ang mapapasok sa katawan.
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Medicines for high blood pressure with a Central effect: mechanisms and clinical relevance High blood pressure (arterial hypertension) is one of the most common chronic diseases worldwide and a major risk factor for cardiovascular diseases such as heart attack, stroke and kidney failure. A special group of antihypertensive drugs acts through Central mechanisms in the Central nervous system (CNS), by reducing the sympathetic over-Excitation, which makes a significant contribution to the increase in blood pressure. Pathophysiological Bases The Arterial hypertension is often associated with increased activity of the sympathetic nervous system. This leads to vasoconstriction, increased heart rate and increased cardiac output are all factors that increase peripheral resistance and blood pressure. Drugs with a Central effect to put this mechanism in the brain stem (especially in the extended marrow, Medulla oblongata), the activity of neurons inhibit the sympathetic deflection of responsibility. The main groups of active substances with a Central action α₂‑Adrenoceptor agonists Clonidine and Methyldopa, the most important representative of this group. They bind to presynaptic α₂‑Adrenoceptors in the CNS, which inhibits the release of norepinephrine. This leads to a reduction in the sympathetic impulses, vasodilation and a reduction of heart rate and blood pressure. Methyldopa is used in particular in the pregnancy as a means of effective and relatively safe drug. Imidazoline Receptor Agonists To this group belongs Moxonidine. Moxonidine acts mainly via imidazoline‑type‑1 receptors (I₁‑receptors) in the Nucleus tractus solitarii. The effect is similar to that of clonidine, however, with lower Central side-effects (less sedation and dryness in the mouth). In addition, Moxonidine shows an insulin sensitizing effect, which may be useful in patients with hypertension and metabolic syndrome advantage. Mechanisms of action at a Glance The Central effect of these substances can be summarised as follows: Inhibition of noradrenergic neurons in the CNS Reduction of peripheral sympathetic activity Decrease in the systemic vascular resistance (SVR) Reduction in heart rate Long-term: regression of vascular changes (Remodelling) Clinical aspects and side effects Although centrally acting antihypertensive agents are effective, they are used in the first line of therapy less frequently than ACE inhibitors, AT₁ receptor blockers or calcium antagonists. Mainly due to the side effect profiles are: Sedation, fatigue, dizziness (by Central damping) Dryness in the mouth (anticholi energy) possible orthostatic hypotension in the case of abrupt Rebound hypertension Discontinuation of clonidine: Conclusion Drugs with a Central effect play an important role in the treatment of arterial hypertension, in particular in special patient groups (e.g., pregnant women with Methyldopa), or in patients in whom standard therapies are not sufficient. The development of newer substances such as Moxonidine has improved the tolerability and clinical application of this class of active substances. An individual Benefit-risk assessment is always required.