Marker for cardiovascular disease
Marker for cardiovascular disease
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Marker for cardiovascular disease Cardiovascular diseases represent one of the main causes of morbidity and mortality in industrialized countries. The early identification of risk markers allows for a preventive Intervention can slow the progression of diseases such as coronary heart disease, congestive heart failure, or stroke or to prevent it. Biochemical Markers A number of biochemical parameters is used disease as a Marker for the diagnosis and prognosis of coronary heart: Troponins (cTnT, cTnI). These proteins are highly specific for myocardial damage. An increase in troponin values in the Serum is considered to be the gold standard for the diagnosis of acute myocardial infarction. Natriuretic peptides (BNP and NT‑proBNP). They are set at an elevated stretch of the cardiac muscle and serve as a Marker for congestive heart failure. High concentrations of BNP and NT‑proBNP correlate with a worse prognosis. C‑reactive Protein (CRP). As a Marker of systemic inflammation, CRP is associated with an increased risk for coronary events. In particular, the high-sensitive CRP (hs‑CRP) is used for risk assessment in patients with moderate cardiovascular risk. Lipid spectrum. Low levels of HDL‑cholesterol, elevated LDL‑cholesterol and triglycerides are known risk factors for atherosclerosis and coronary heart disease. Homocysteine. Increased homocysteine concentrations in the blood are associated with an increased risk for vascular diseases, although their role as an independent risk marker is still under discussion. Imaging Markers In addition to biochemical parameters, imaging techniques play an important role in the identification of structural and functional changes: Echocardiography. Provides information about the wall motion, ventricular function, and heart valve defects. Coronary computed tomography (CT). The detection of Calcifications in the coronary arteries (Calcium Scoring), which is an indicator of subclinical atherosclerosis allows. Magnetic resonance imaging (MRI) of the heart. A high-resolution representation of the myocardium provides scars, inflammation, and other pathological changes. Genetic Markers Advances in genetics have shown that certain gene variants may increase the risk for cardiovascular diseases. Polymorphisms in genes for Lipid metabolism, blood coagulation or blood pressure regulation, are intensively explored. For example, variants in the APOE are associated with increased LDL‑cholesterol levels and atherosclerosis risk. Conclusion Dieuführliche analysis of biochemical, imaging and genetic markers allows for a differentiated risk assessment and individual therapy in cardiovascular diseases. The combination of different markers increases the predictive power and allows early preventive treatment. Further research is necessary to identify new markers and to optimize existing test procedures. Would you like me to make a certain section in greater detail or further information to a specific Marker to add?
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Ang mga modernong gamot sa pag-imprenta ay hinahati sa 10 iba't ibang grupo ayon sa kanilang mekanismo ng pagkilos. Pagkatapos suriin ng doktor ang mga reklamo ng pasyente at ang resulta ng mga pagsusuri, nagrereseta siya ng isa o higit pang gamot, na hindi dapat baguhin nang mag-isa. Ang mga gamot sa puso at daluyan ng dugo ay hindi kabilang sa mga puwedeng irekomenda sa kaibigan. Ang maling desisyon ay maaaring magdulot ng malungkot na kahihinatnan. Lahat ng gamot na pampababa ng presyon ng dugo ay kailangan ng reseta. Sa artikulong ito, tinitingnan natin ang kanilang modernong klasipikasyon base sa mga aktibong sangkap at sa paraan ng epekto nito sa katawan. Ang mga modernong gamot sa pag-imprenta ay hinahati sa 10 iba't ibang grupo ayon sa kanilang mekanismo ng pagkilos. Pagkatapos suriin ng doktor ang mga reklamo ng pasyente at ang resulta ng mga pagsusuri, nagrereseta siya ng isa o higit pang gamot, na hindi dapat baguhin nang mag-isa. Ang mga gamot sa puso at daluyan ng dugo ay hindi kabilang sa mga puwedeng irekomenda sa kaibigan. Ang maling desisyon ay maaaring magdulot ng malungkot na kahihinatnan. Lahat ng gamot na pampababa ng presyon ng dugo ay kailangan ng reseta. Sa artikulong ito, tinitingnan natin ang kanilang modernong klasipikasyon base sa mga aktibong sangkap at sa paraan ng epekto nito sa katawan.
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